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A case of Maxillary Sinus Plasmacytoma and Analysis of Cellular Biological Features

The bulletin of the Yamaguchi Medical School Volume 49 Issue 3-4 Page 107-113
published_at 2002-12
A020049000309.pdf
[fulltext] 264 KB
Title
A case of Maxillary Sinus Plasmacytoma and Analysis of Cellular Biological Features
Creators Ita Masamichi
Creators Okafuji Masaki
Creators Noutomi Yasuyuki
Creators Saito Yukoh
Creators Sasaki Kohsuke
Source Identifiers
Creator Keywords
Plasmacytoma Maxillary sinus DNA cotent comparative genomic hybridization
Extramedullary plasmacytoma is a rare malignant tumor that generally arises in the head and neck region. We encountered a plasmacytoma located in the maxilla, maxilllary sinus, and ethmoidal sinuses. The tumor was composed of premature cells showing positive staining for λlight chain immunoglobulin. Several types of examination, including M protein analysis, reled out multiple myeloma. After a debulking operation, a total of 50 Gy of radiation failed to shrink the tumor. To prevent the tumor from progressing to multiple myeloma, the patient underwent chemotherapy. After this treatment, the tumor showed no growth. Flow cytometry and comparative genomic hybridization studies showed the tumor DNA to be diploid, containing few chromosomal aberrations. On the basis of these findings, it was thought that the tumor malignancy of plasmacytoma might be relevant to DNA ploidy pattern and chromosomal aberration.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 2002-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部