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Endocrinological Analyses of Mental Disorders in Adolescence: Changes of Steroid Metabolite (Urinary 17KS) Levels in the Urine

The bulletin of the Yamaguchi Medical School Volume 39 Issue 1-2 Page 13-20
published_at 1991-06
A020039000103.pdf
[fulltext] 588 KB
Title
Endocrinological Analyses of Mental Disorders in Adolescence: Changes of Steroid Metabolite (Urinary 17KS) Levels in the Urine
Creators Mashimoto Shigeki
Creators Hirano Hitoshi
Creators Miyoshi Akira
Creators Ikeda Toshimi
Creators MIzuki Yasushi
Creators Yamada Michio
Source Identifiers
Creator Keywords
Periodical psychosis Adolescence Urinary 17KS Androsterone Etiocholanolone
Adolescence is expected to have different endocrinological patterns from adults. In this study, we monitered the urinary 17KS fractions of healthy adolescent volunteers (12-18 years old) and patients with psychological disorders (13-18 years old). The ratio of androsterone to etiocholanolone (A/E) in the male adolescent volunteers was nearly the same as that in adult males, and A/E in the female adolescent volunteers was lower than adult females. The ratios in adolescent patients did not differ significantly from the levels in the normal volunteers, but there was a clear tendency between patients' symptoms and level of A/E : patients with higher A/E had aggressive symptoms (e.g., violence to family), and patients with lower A/E had such symptoms as anxiety, depression, common neurosis, and dissociative disorders. In order to evaluate the patient's true condition, a physically index which represents different mental state should be established. Urinay fractions 17KS and A/E could be useful in understanding the mental conditions of patients and in prescribing appropriate therapy.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1991-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部