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Intraoperative Radiation Therapy for Carcinoma of the Pancreas

The bulletin of the Yamaguchi Medical School Volume 38 Issue 3-4 Page 105-109
published_at 1991-12
A020038000310.pdf
[fulltext] 875 KB
Title
Intraoperative Radiation Therapy for Carcinoma of the Pancreas
Creators Ebe Kazuyu
Creators Nishikawa Eiichi
Creators Suda Hiroki
Creators Honma Yutaka
Creators Kawamura Mitsutoshi
Creators Okada Morihisa
Creators Karino Yuichi
Creators Nakada Taishi
Creators Nakanishi Takashi
Creators Uchiyama Tetsuzi
Creators Hamanaka Yuichiro
Creators Suzuki Takashi
Source Identifiers
Creator Keywords
Intraoperative radiation therapy (IOR) Carcinoms Pancreas Intraarterial infusion Radiosensitizer RK28 Rabbit VX2 tumor
Intraoperative radiation therapy (IOR) was performed on 13 patients with carcinoma of the pancreas. Seven cases were resectable and 6 cases wre unresectable. Tumor regression was observed in 5 of 6 unresectable tumors. Relief of abdominal pain was achieved in all 6 cases. The median survival of 13 patients was 145 dyas. Intraarterial infusion of hypoxic cell radiosensitizer RK28 was examined as a model of future clinical application for IOR using a rabbit VX2 tumor system. The tumor regression slopes were statistically different (P<0.01). But the difference in long-term survival was not statistically significant (P<0.10). Intraarterial infusion of RK28 is clinically promising in the future.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1991-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部