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Effects of Temperature on Membrane in Sheep Heart Pubkinje Fibers Currents

The bulletin of the Yamaguchi Medical School Volume 19 Issue 1-2 Page 31-42
published_at 1972-06
A020019000104.pdf
[fulltext] 3.05 MB
Title
Effects of Temperature on Membrane in Sheep Heart Pubkinje Fibers Currents
Creators Shibata Jiro
Source Identifiers
Creator Keywords
voltage clamp slow inward current voltage-current relationship plateau phase Ca++
Influences of temperature (32℃-38℃) on membrane currents of sheep heart purkinje fiber were examined by means of voltage clamp technique which was done by double microelectrode impalement into a a short strip of the fiber. A slowly decreasing inward current following to an initial rapid inward current was observed in Na-Tyrode solution when the membrane potential was held between-20mV and -40mV. In Na-free solution (Choline-Tyrode), only outward current which gradually decays with the progress of time was observed in depolarizing clamp. The time course of slow inward current is shrtiened in high temperature, but not much prolonged in low temperature. The time course of outward current is prolonged in low temperature but a little shortened in high temperature is mainly caused by the early disappearance of slow inward current carried by Na+ and the prolongation is mainly coused by the slow decay of the outward current carried by K+.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1972-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部