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Blastogenic Property of Lectin from Semen Jequirity (Abrus precatorius L)

The bulletin of the Yamaguchi Medical School Volume 28 Issue 1-2 Page 27-34
published_at 1981-06
A020028000104.pdf
[fulltext] 981 KB
Title
Blastogenic Property of Lectin from Semen Jequirity (Abrus precatorius L)
Creators Kato Seiji
Creators Awaya Kazuhiko
Creators Nakatsukasa Yoshihiko
Creators Okuda Yoshihiro
Source Identifiers
Creator Keywords
abrus lectin lymphocyte blastogenesis
The skin reactions to purified protein derivative (PPD), phytohemagglutinin (PHA) and polysacchride antigens streptococcal hemolyticus (PS-E), were depressed in the initial stage of the patients and markedly depressed in the end stage. The number of T-cells in peripheral blood decreased with progress of illness, but the number of PHA-blastoid cells and active T-cells increased sometimes in the end stage. It suggests that these factors as well as skin tests are useful parameters for evaluation of the cellular immune status of the patients with primary liver carcinoma. The host's immune status was impaired frequently either by the disease itself or by chemotherapy. In cases receiving chemotherapy in combination with the administration of OK-432, the depressd skin reaction to PS-E improved often. These findings suggest that the administration of OK-432 affect the host and that reslut of this skin test is useful as a parameter to determine the method and period of OK-432 administraion and to judge its effectiveness.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1981-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部