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Our 10-year Experience in the Management of Newborn Infants with Multiple Congenital Anomalies

The bulletin of the Yamaguchi Medical School Volume 47 Issue 1-2 Page 21-26
published_at 2000-06
A020047000105.pdf
[fulltext] 555 KB
Title
Our 10-year Experience in the Management of Newborn Infants with Multiple Congenital Anomalies
Creators Kuga Takayuki
Creators Taniguchi Satoshi
Creators Inoue Takashi
Creators Zempo Nobuya
Creators Esato Kensuke
Source Identifiers
Creator Keywords
congenital anomalies multiple congenital anomalies management prenatal diagnosis /chromosomal abnormalities quality of life
Purpose : The incidence of multiple congenital anomalies has increased as a result of advances in prenatal and prenatal treatment. A review of all infants born with more than two congenital anomalies was conducted to identify the clinical feature.Methods : Between January, 1989 and December, 1998, a total of 35 neonates with multiple congenital anomalies were referrred to Yamaguchi University Hospital. The Combination of anomalies, manalies, management and clinical course, prenatal diagnosis and treatment, chromosomal anomalies, outcome, and quality of life these infants were examined retrospectively.Results : Of these 35 infants, 9(25.7%) had chromosomal abnormalities in the form of trisomy 21 in 8, and trisomy 18 in 1. Prenatal diagnoses were established in 10 infants (28.6%) and a fetal treatment was preformed in 1. There were four deaths (11.4%) caused by trisomy 18, pulmonary hypoplasia, or cardiac anomalies. Among the survivingpatients, two(6.5%) suffered from mental retardation caused by trisomy 21 or a brain anomaly. A total of 18 children (58.1%) required as mental training, defecation training, or medication review. Conclusion : Approximately one fourth of infants with multiple congenital anomalies had chromosomal abnormalities. Chromosomal abnomalities or cardio-pulmonary anomalies were death causes. More than half of children required long-term forrow-up. We should aim to provide well-plannned management to promote good long-term quality of life of neonates with multiple congenital anomalies.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 2000-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部