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Flow Cytometric Study on Tumor Antigen TA-4 in Uterine Cervical Squamous Cells

The bulletin of the Yamaguchi Medical School Volume 31 Issue 1 Page 7-1
published_at 1984-12
A020031000102.pdf
[fulltext] 1.45 MB
Title
Flow Cytometric Study on Tumor Antigen TA-4 in Uterine Cervical Squamous Cells
Creators Sasaki Kohsuke
Creators Nagai Michihiro
Creators Kato Hiroshi
Creators Torigoe Tadashi
Creators Nagamine Yoshiaki
Creators Takahashi Manabu
Source Identifiers
Creator Keywords
Flow cytometry Tumor antigen Squamous cell carcinoma Uterine cervical cancer
Flow cytometric analysis was made of a tumor-antigen, TA-4, in cells from squamous cell carsinoma of the utrine cervix. The cells were stained by the indirect immunofluorescent antibody technique using a rabbit antibody specific to TA-4 and fluorescein isothiocyanate conjugated anti-rabbit IgG antibody. FCM histograms of the carcinoma cells showed a broad but conspicuous pesk with intense fluorescence pattern not seen in normal squamous epithelium. Would be possible to distinguish malignant from non-malignant cells of the uterine cervix it by the FCM analysis. Possible application of the technique to cytological screening of cervical cancer is discussed.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1984-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部