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Evaluation of Frozen Section Diagnosis and Rapid Intraoperative Flow Cytometric Analysis of Oral and Maxillofacial Lesions

The bulletin of the Yamaguchi Medical School Volume 37 Issue 3-4 Page 113-117
published_at 1990-12
A020037000308.pdf
[fulltext] 426 KB
Title
Evaluation of Frozen Section Diagnosis and Rapid Intraoperative Flow Cytometric Analysis of Oral and Maxillofacial Lesions
Creators Matsumura Kouji
Creators Tsuji Tatsuo
Creators Nakashima Kasuke
Creators Sasaki Kohsuke
Creators Hiraoka Fumiko
Creators Shinozaki Fumihiko
Source Identifiers
Creator Keywords
Frozen section diagnosis Flow cytometry DNA aneuploidy
Frozen section diagnoses of oral and maxillofacial lesions were performed in 60 cases at the Yamaguchi University Hospital over the course of 3 years. Frozen section diagnoses were mainly used to determine the surgical margins (68.3%) and/or lymph node metastasis (71.7%). Only 20% of those frozen sections were used to obtain pathological diagnoses of lesions, which were uncertain diagnoses before the operation. The average number of frozen sections per operation was 4.4, with 14 being the most. Ninety-eight percent of the frozen section diagnoses were consistent with the final permanent section diagnoses. In some of these cases, a rapid measurement of DNA patterns, using flow sytometry (FCM), was performed. The incidence of DNA patterns, using flow cytometry (FCM), was performed. The incidence of DNA aneuploidy was found, we almost always diagnosed that section as to be malignant. Therefore, the measurement of DNA ploidy patterns would be useful in supporting the frozen section diagnoses.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1990-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部