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Immunohistochemical Demonstration of Nerves Containing Protein Gene Product 9.5 (PGP 9.5) and Neuropeptides in the Mouse Kidney

The bulletin of the Yamaguchi Medical School Volume 44 Issue 1-2 Page 1-9
published_at 1997-06
A020044000101.pdf
[fulltext] 2.85 MB
Title
Immunohistochemical Demonstration of Nerves Containing Protein Gene Product 9.5 (PGP 9.5) and Neuropeptides in the Mouse Kidney
Creators Takeuchi Keiji
Source Identifiers
Creator Keywords
Protein gene product 9.5-Neuropeptide Y-Calcitonin gene-related peptide-Substance P-Kidney innervation
The immunoreactivity for protein gene product (PGP) 9.5, a neuronal marker, was examined in the mouse kidney. Immunoreactivities for neuropeptide Y (NPY), calcitonin gene-related peptide (CCRP),substance P (SP) and vasoactive intestinal polypaptide (VIP) were also studied.Nerve fibers with PGP 9.5 immunoreactivity were widely recognized in all segments of the renal vascular system,i.e.,in the interlobar,arcuate,and interlobar arteries and veins,in the afferent and efferent arterioles,and in the vasa recta of the outer stripe of the outer zone of the medulla.In the renal tebules, there ware also a few varicose terminals showing PGP 9.5 immunoreactivity.NPY-immunoreactive fibers occurred widly in the renal vascular system forming a plexus.Moderate number of CGRP-immunoreactive fibers and a few SP-immunoreactive fivers,which seemd to be co-localized partly,were distributed mainly in the interlobar and adcuate arteries.No VIP-positive nerves were recognizable.Each positive type of nerve fibers shouwed an unique distribution and seemed to act differently in the various branches of the renal vascular system.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1997-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部