Inoue Takeshi
Affiliate Master
Yamaguchi University
Schools
医学部附属病院
Aprepitant relieves chemotherapy-induced inappetance in colorectal cancer patients in the acute phase of mod-erate emetogenic chemotherapy: An observational study based on self-report diaries
The bulletin of the Yamaguchi Medical School Volume 60 Issue 1-2
Page 19-26
published_at 2013
Title
Aprepitant relieves chemotherapy-induced inappetance in colorectal cancer patients in the acute phase of mod-erate emetogenic chemotherapy: An observational study based on self-report diaries
Creators
Furuya Takumi
Creators
Fujimoto Takuya
Creators
Kamimura Yoshio
Creators
Takemoto Norikazu
Creators
Hayashi Hideto
Creators
Yahara Noboru
Creators
Saeki Toshihiro
Creators
Hayashi Hiroto
Source Identifiers
Creator Keywords
antiemesis
palonosetron
food intake
water intake
Background: The novel drugs aprepitant (APR) and palonosetron are rec- ommended for the treatment of chemotherapy-induced nausea and vomiting. Here, we assessed the effects of these antiemetics using a self-report diary.Methods: This was a retrospective observational study based on data from 87 pa- tients spectively collected in 222 self-report diaries. We assessed the effect of vomiting and nausea on the patients'quality-of-life, and food and water intake. A“no event”was treated as a favorable outcome. We compared the rates of no event be-tween the first course of chemotherapy and subsequent courses, as well as among the different emetogenic risks and post-chemotherapy phases. We also studied the effect of APR in a subgroup of colorectal cancer patients receiving moderate emetogenic chemotherapy.Results: Nearly 90% of patients reported that the vomiting and nausea did not af- fect their quality-of-life
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University School of Medicine
Date Issued
2013
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部附属病院