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Nao Tomoko

Affiliate Master Yamaguchi University

Update Date (<span class="translation_missing" title="translation missing: en.view.desc">Desc</span>)
山口医学 Volume 66 Issue 2 pp. 89 - 96
published_at 2017-05-01
Background The lipid-lowering therapy by statins may stabilize and reduce coronary plaques. We compare the effect of strong or moderate statins on the coronary plaque characteristics by using 64-slice multidetector computed tomography (MDCT). Methods and Results We analyzed 13 subjects with non-calcified coronary plaques(NCP)as determined by MDCT. Pitavastatin(PTV:2mg/day)or pravastatin(PRA:10mg/day)were randomly administered. MDCT were performed at 0, 6 and 12 months after lipid-lowering therapy. In PTV group(n=6),CT density of NCP increased by 35.6 ± 28.8 HU after 6 months(p=0.037)and by 30.6 ± 29.8 HU after 12 months(NS).NCP area was decreased by 35.9 ± 15.2 % after 6 months and by 41.0 ± 16.5 % after 12 months(both P=0.001).In PRA group(n=7),CT density of NCP did not significantly increased after 6 months(NS)and after 12 months(NS).NCP area was not significantly decreased at 6 months(NS),but decreased by 23.1 ± 16.7 % at 12 months(P=0.001). Conclusions Serial CT angiography revealed that the regression of NCP occurs rapidly by strong lipid lowering therapy compared to the moderate statin therapy.
Creators : Nao Tomoko Miura Toshiro Yoshimura Masayuki Fujimura Tatsuhiro Nakashima Yoshiteru Okada Munemasa Matsunaga Naofumi Yano Masafumi Publishers : 山口大学医学会
European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology Volume 13 Issue 1 pp. 29 - 36
published_at 2011-01
Creators : Kobayashi Shigeki Susa Takehisa Tanaka Takeo Wada Yasuaki Okuda Shinichi Doi Masahiro Nao Tomoko Yoshiga Yasuhiro Yamada Jutaro Okamura Takayuki Ueyama Takeshi Kawamura Syuji Yano Masafumi Matsuzaki Masunori Publishers : Elsevier | European Society of Cardiology
European journal of radiology Volume 80 Issue 2 pp. 336 - 341
published_at 2011-11
Creators : Okada Munemasa Nakashima Yoshiteru Shigemoto Youko Matsunaga Naofumi Miura Toshiro Nao Tomoko Sano Yuichi Narazaki Akiko Kido Shoji Publishers : G. Thieme
Circulation Journal Volume 78 Issue 3 pp. 772 - 774
published_at 2013
Creators : Tateishi Hiroki Okamura Takayuki Yamada Jutaro Nao Tomoko Maeda Takao Oda Takamasa Nakamura Takeshi Miura Toshiro Matsuzaki Masunori Yano Masafumi Publishers : Japanese Circulation Society
Cardiology (Switzerland) Volume 127 Issue 2 pp. 105 - 113
published_at 2014-01
Creators : Kobayashi Shigeki Murakami Wakako Myoren Takeki Tateishi Hiroki Okuda Shinichi Doi Masahiro Nao Tomoko Wada Yasuaki Matsuzaki Masunori Yano Masafumi Publishers : Karger