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Enoki Tadahiko

Affiliate Master Yamaguchi University

Detection of K-ras Codon 12 Mutation in the Portal Blood during Surgery for Pancreatic Carcinoma

The bulletin of the Yamaguchi Medical School Volume 45 Issue 1-4 Page 51-56
published_at 1998-12
A020045000108.pdf
[fulltext] 1.66 MB
Title
Detection of K-ras Codon 12 Mutation in the Portal Blood during Surgery for Pancreatic Carcinoma
Creators Enoki Tadahiko
Creators Morita Nobuyoshi
Creators Inokuchi Tomohiro
Creators Tsushimi Takahiro
Creators Hayashi Daisuke
Creators Okamura Keiji
Creators Shinagawa Hidetaka
Creators Orita Masahiko
Creators Noshima Shinji
Creators Esato Kensuke
Source Identifiers
Creator Keywords
K-ras codon 12 mutation liver metastasis pancreas carcinoma portal blood
Background and Aim : It is well known that pancreatic adenocarcinomas harber K-ras gene point mutations, which are frequently restricted to codon 12. Thus, the detection of K-ras codon 12 mutations in pancreatic or duodenal juice may did in the diagnosis of pancreatic adenocarcinomas. In the present study, we investigated whether or not portal blood collected during surgery for pancreatic adenocarcinoma contains the K-ras codon 12 mutation. Methods : During radical resection for pancreatic adenocarcinoma, 10ml of portal blood was taken twice
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1998-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部