Hirano Hitoshi
Affiliate Master
Yamaguchi University
Endocrinological Analyses of Mental Disorders in Adolescence: Changes of Steroid Metabolite (Urinary 17KS) Levels in the Urine
The bulletin of the Yamaguchi Medical School Volume 39 Issue 1-2
Page 13-20
published_at 1991-06
Title
Endocrinological Analyses of Mental Disorders in Adolescence: Changes of Steroid Metabolite (Urinary 17KS) Levels in the Urine
Creators
Mashimoto Shigeki
Creators
Miyoshi Akira
Creators
Ikeda Toshimi
Creators
MIzuki Yasushi
Creators
Yamada Michio
Source Identifiers
Creator Keywords
Periodical psychosis
Adolescence
Urinary 17KS
Androsterone
Etiocholanolone
Adolescence is expected to have different endocrinological patterns from adults. In this study, we monitered the urinary 17KS fractions of healthy adolescent volunteers (12-18 years old) and patients with psychological disorders (13-18 years old). The ratio of androsterone to etiocholanolone (A/E) in the male adolescent volunteers was nearly the same as that in adult males, and A/E in the female adolescent volunteers was lower than adult females. The ratios in adolescent patients did not differ significantly from the levels in the normal volunteers, but there was a clear tendency between patients' symptoms and level of A/E : patients with higher A/E had aggressive symptoms (e.g., violence to family), and patients with lower A/E had such symptoms as anxiety, depression, common neurosis, and dissociative disorders. In order to evaluate the patient's true condition, a physically index which represents different mental state should be established. Urinay fractions 17KS and A/E could be useful in understanding the mental conditions of patients and in prescribing appropriate therapy.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1991-06
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部