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Hinoda Yuji

Affiliate Master Yamaguchi University

Expression of an Immunotherapeutic Target Antigen 17-1A for Colorectal Cancer in Multiple Myeloma

The bulletin of the Yamaguchi Medical School Volume 47 Issue 1-2 Page 17-20
published_at 2000-06
A020047000104.pdf
[fulltext] 326 KB
Title
Expression of an Immunotherapeutic Target Antigen 17-1A for Colorectal Cancer in Multiple Myeloma
Creators Hinoda Yuji
Creators Hayashi Toshiaki
Creators Takahashi Tohru
Creators Adachi Masaaki
Creators Imai Kohzoh
Source Identifiers
Creator Keywords
antigen 17-1A colorectal cancer monoclonal antibody multiple myeloma immunotherapy
A colorectal cancer-associated 17-1A antigen is an effective therapeutic target with monoclonal antibody (mAb) for preventing the recurrence of colorectal cancer. We evaluated its expression in myeloma cell lines and bone marrow cells from patients with multiple myeloma or primary macroglobulinemia by indirect immunofluorescence assays. Antigen 17-1A was shown positive in 3 out of 4 cell lines tested and in 8 out of 9 bone marrow cell specimens including 6 multiple myelomas, one IgG-producing chronic lymphoproliferation and 2 primary macroglobulinemias. These data suggest that adminisration of mAb 17-1A may be a new feasible immunotherapy to those indolent, but incurable diseases.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 2000-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部