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Tanaka Nobuyuki

Affiliate Master Yamaguchi University

Effect of Absolute Ethanol Injection into Solid Tumors Estimated by Xe Tumor Blood Flow on a Mouse and a Human

The bulletin of the Yamaguchi Medical School Volume 35 Issue 3-4 Page 63-67
published_at 1988-12
A020035000305.pdf
[fulltext] 2.74 MB
Title
Effect of Absolute Ethanol Injection into Solid Tumors Estimated by Xe Tumor Blood Flow on a Mouse and a Human
Creators Ebe Kazuyu
Creators Suda Hiroki
Creators Kuramitu Tatuya
Creators Honma Yutaka
Creators Okada Morihisa
Creators Hatanaka Masao
Creators Tanaka Nobuyuki
Creators Suga Kazuyoshi
Creators Sasai Kazuhiko
Creators Tanaka Rikuo
Creators Yokoyama Takashi
Creators Nakanishi Takashi
Creators Nishihara Sadamitsu
Creators Utumi Hiromot
Creators Yamada Norimasa
Source Identifiers
Creator Keywords
Absolute Ethanol Injection Xe Tumor Blood Flow Mouse Human
The tumor blood flow was calculated by Xe clearance curves. Absolute Ethanol injection shuts off the tumor blood flow very powerfully. In the case of a nude mouse, 0.05 ml of absolute ethanol decreased the tumor blood flow to 60% and 0.10 ml of it decreased to 11% markedly. The latter tumor fell and cured 2 weeks later, but the former still grew. In a human, two cases who had mitastatic tumors st the chest walls were treated in the same way. In the first case, 20 ml of it was injected and tumor blood flow was decreased to 27%. In the second case, 25 ml of it was injected and the tumor blood flow was decreased to 2.4%. The enhanced Computed Tomography scans showed massive tumor necrosis occurred a week later in the both cases. The decreased tumor blood flow correlated to the tumor responses to absolete ethanol injections on both a mouse and a human.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1988-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部