Sasaki Kohsuke
Affiliate Master
Yamaguchi University
Relationship between C－MYC Expression and the Cell Cycle in HL－6０ Cells －Flow Cytometric Analysis－
The bulletin of the Yamaguchi Medical School Volume 33 Issue 1
Page 9-12
published_at 1986-12
Title
Relationship between C－MYC Expression and the Cell Cycle in HL－6０ Cells －Flow Cytometric Analysis－
Source Identifiers
Creator Keywords
Oncogene
c-myc protein
Cell cycle
HL-60
Flow cytometry
By flow cytometric measurement of cellular DNA, c-myc protein and cell volume, we attempted to assess the relationship between c-myc gene expression and the cell cycle in exponentially growing human promyrlocytic leukemia cell line (HL-60). The protein product of c-myc gene was stained by an indirect immunofluorescence method using a specific antiserum to human c-myc protein. Bivariate distributions of cellular DNA, the c-myc protein contents and cell volume demonstrated the direct evidence that the c-myc protein increases with the progression of the cell cycle and then is halved by cell division.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1986-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594273
Schools
医学部