γ-Oryzanol, a unique ingredient specific to brown rice, effectively restores mild cognitive impairment (MCI) in obese aged mice by ameliorating microglial inflammation and promoting neurogenesis in hippocampus : Novel therapeutic insight into obesity-associated MCI
Journal of Food Bioactives Volume 34
Page 38-47
published_at 2026-06-30
Supplemental Data : https://public.oa.kenkyu.yamaguchi-u.ac.jp/45be1304-92d5-48dc-95cd-463d48fd79c3
Title
γ-Oryzanol, a unique ingredient specific to brown rice, effectively restores mild cognitive impairment (MCI) in obese aged mice by ameliorating microglial inflammation and promoting neurogenesis in hippocampus : Novel therapeutic insight into obesity-associated MCI
Creators
Nomura Ikumi
Creators
Kinjo Ayano
Creators
Murayama Yuko
Creators
Horiguchi Chie
Creators
Kozuka Chisayo
Creators
Teruya Taiki
Creators
Uema Tsugumi
Creators
Nagai Tomoko
Creators
Shimabukuro Michio
Creators
Takayama Chitoshi
Creators
Matsushita Masayuki
Creators
Abe Keiko
Creators
Masuzaki Hiroaki
Source Identifiers
[PISSN] 2637-8752
[EISSN] 2637-8779
Creator Keywords
γ-Oryzanol
Mild cognitive impairment (MCI)
Hippocampus
Neurogenesis
Obesity
Languages
eng
Resource Type
journal article
Publishers
Tsinghua University Press
Date Issued
2026-06-30
Rights
© The author(s) 2025. Publishing Services by Tsinghua University Press()
The articles published in this open access journal are distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)()
Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)
File Version
Version of Record
Access Rights
open access
Relations
[isIdenticalTo]
10.26599/JFB.2026.95034446
[isSupplementedBy]
[URI]https://public.oa.kenkyu.yamaguchi-u.ac.jp/45be1304-92d5-48dc-95cd-463d48fd79c3
Funding Refs
Japan Society for the Promotion of Science
[crossref_funder]https://doi.org/10.13039/501100001691
Award
Molecular mechanism of acetylcholine signaling in the brain and improvement of addiction and dementia by functional components of brown rice
20K08912
Funding Refs
Japan Society for the Promotion of Science
[crossref_funder]https://doi.org/10.13039/501100001691
Award
Molecular mechanism in the brain of the change in food preference associated with rapid weight loss after obesity
18K11079
Funding Refs
Japan Agency for Medical Research and Development
Award
重症食物アレルギー患者への管理および治療の安全性向上に関する研究
19ek0410049