Antianxiety Effect of Ehtyl Loflazepate， CM6912， Assessed by Frontal Medline Theta Activity in Man
The bulletin of the Yamaguchi Medical School Volume 32 Issue 1
Page 71-77
published_at 1985-12
Title
Antianxiety Effect of Ehtyl Loflazepate， CM6912， Assessed by Frontal Medline Theta Activity in Man
Creators
Mizuki Yasushi
Creators
Hamasaki Junko
Creators
Ushijima Itsuko
Creators
Yamada Michio
Creators
Tanaka Masatoshi
Creators
Inanaga Kazutoyo
Source Identifiers
Creator Keywords
benzodiazepines
diazepam
CM6912
antianxiety effect
frontal midline theta activity (Fmθ）
The theta activity which appears in the frontal midline area during performance of mental tasks been designated as Fmθ. In the present atudy, the potency of CM6912 as an anixiolytic was investigated using Fmθas compared with diazepam. Sixteen male university students were given placebo, diazepam 5 mg, CM6912 2 mg and 4 mg in a double-blind, crossover design. Scores were made on the state anxiety scale of Spielberger`s State Trait Anxiety Inventory (STAI), EEDs were recorded before and during performance of an arithmetic addition. The test was repeated twice, before and 1 hr after drug administration. Placebo increased Fmθ
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1985-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部