A case of Maxillary Sinus Plasmacytoma and Analysis of Cellular Biological Features
The bulletin of the Yamaguchi Medical School Volume 49 Issue 3-4
Page 107-113
published_at 2002-12
Title
A case of Maxillary Sinus Plasmacytoma and Analysis of Cellular Biological Features
Creators
Ita Masamichi
Creators
Okafuji Masaki
Creators
Noutomi Yasuyuki
Creators
Saito Yukoh
Source Identifiers
Creator Keywords
Plasmacytoma
Maxillary sinus
DNA cotent
comparative genomic hybridization
Extramedullary plasmacytoma is a rare malignant tumor that generally arises in the head and neck region. We encountered a plasmacytoma located in the maxilla, maxilllary sinus, and ethmoidal sinuses. The tumor was composed of premature cells showing positive staining for λlight chain immunoglobulin. Several types of examination, including M protein analysis, reled out multiple myeloma. After a debulking operation, a total of 50 Gy of radiation failed to shrink the tumor. To prevent the tumor from progressing to multiple myeloma, the patient underwent chemotherapy. After this treatment, the tumor showed no growth. Flow cytometry and comparative genomic hybridization studies showed the tumor DNA to be diploid, containing few chromosomal aberrations. On the basis of these findings, it was thought that the tumor malignancy of plasmacytoma might be relevant to DNA ploidy pattern and chromosomal aberration.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
2002-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部