Monoclonal Antibody May Recognize Highly Evolutionary Conserved Molecule - An Immunocytochemical Study -
The bulletin of the Yamaguchi Medical School Volume 37 Issue 3-4
Page 89-93
published_at 1990-12
Title
Monoclonal Antibody May Recognize Highly Evolutionary Conserved Molecule - An Immunocytochemical Study -
Creators
Tomonaga Susumu
Creators
Fujikura Yoshihisa
Creators
Kuniki Hiromichi
Creators
Ito Kazuo
Creators
Fukumoto Tetsuo
Source Identifiers
Creator Keywords
Monoclonal antibody
Evolutionary conserved antigen
Thymocytes
Brain
Immunocytochemistry
A monoclonal antibody, UB-13 which may react highly evolutionary conserved molecule was established. The antibody was made immunizing mice with homogenized skate brain and then cloning both with rat and skate thymocytes. The reactivity of the antibody was analyzed immunocytochemically using the indirect immunocytochemical method. The UB-13 appeared to be reactive with thymocytes of all species of vertebrates examined, such as fish, frog, turtle, chicken and rat. Cells of the nervous system, some populatons of lymphoid cells are also positive with UB-13 immunostaining. These findings strongly suggest that UB-13 is a unipue monoclonal antibody which recognizes evolutionary conserved molecule.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1990-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部