Flow Cytometric Study on Tumor Antigen TA－4 in Uterine Cervical Squamous Cells
The bulletin of the Yamaguchi Medical School Volume 31 Issue 1
Page 7-1
published_at 1984-12
Title
Flow Cytometric Study on Tumor Antigen TA－4 in Uterine Cervical Squamous Cells
Creators
Nagai Michihiro
Creators
Kato Hiroshi
Creators
Torigoe Tadashi
Creators
Nagamine Yoshiaki
Creators
Takahashi Manabu
Source Identifiers
Creator Keywords
Flow cytometry
Tumor antigen
Squamous cell carcinoma
Uterine cervical cancer
Flow cytometric analysis was made of a tumor-antigen, TA-4, in cells from squamous cell carsinoma of the utrine cervix. The cells were stained by the indirect immunofluorescent antibody technique using a rabbit antibody specific to TA-4 and fluorescein isothiocyanate conjugated anti-rabbit IgG antibody. FCM histograms of the carcinoma cells showed a broad but conspicuous pesk with intense fluorescence pattern not seen in normal squamous epithelium. Would be possible to distinguish malignant from non-malignant cells of the uterine cervix it by the FCM analysis. Possible application of the technique to cytological screening of cervical cancer is discussed.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1984-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部