On Syndrome with Periodic, Episodic Manic Condition as the Primary Symptom
The bulletin of the Yamaguchi Medical School Volume 25 Issue 1-2
Page 63-67
published_at 1978-06
Title
On Syndrome with Periodic, Episodic Manic Condition as the Primary Symptom
Creators
Yamada Michio
Creators
Ota Tamio
Creators
Yamaoka Hideki
Creators
Matsumoto Takafumi
Source Identifiers
The tolerance of four strains of Pseudomonas aeruginosa to chlorhexidine increased 8 to 32 times during 21 passages every other day in nutrient broth containing subinhibitory concentrations of the disinfectant. The cells from the 30th subcultures died more slowly in either 0.5 or 0.02% solution of chlorhexidine than those of the parent strains. Likewase, the minimal inhibitory concentrations were greater with acrinol for the bacteria from the 30th subcultures than for those of the parent strains. On the other hand, no significant differences were observed between the parent strains and those from the 30th subcultures in minimal inhibitory concentrations of ampicillin, carbenicillin, dibekacin, amikacin, polymixin B and benzalkonium chloride. The bacteria that had acquired resistance after 30 subcultures in the presence of chlorhexidine were further subcultured for another 30 passages in a disinfectant-free nutrient broth. In three of the four strains tested, the acquired resistance to chlorhexidine was reduced to one-fourth to one-eighth, but it was unchanged in one strain.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1978-06
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部