Hepatic fibrogenesis and carcinogenesis

The bulletin of the Yamaguchi Medical School Volume 43 Issue 3-4 Page 45-48

published_at 1996-12

A020043000301.pdf

[fulltext] 1.68 MB

Title

Hepatic fibrogenesis and carcinogenesis

Creators Sakaida Isao

Source Identifiers

Creator Keywords

fibrosis stellate cell proly 4-hydroxylase inhibitor preneoplastic lesion glutathione S-transferase placental form choline-deficient L-amino acid-defined diet

The stellate cell plays a central role in liver fibrosis in human liver diseases as well as in experimantal animal models. Direct prevention of liver fibrosis by a newly synthesized proly 4-hydroxylase inhibitor (HOE 077) reduced the number of preneoplastic lesions in rat liver. Fibrosupperession may limit the development of hepatic neoplasms.

Subjects

医学 ( Other)

Languages eng

Resource Type departmental bulletin paper

Publishers Yamaguchi University Graduate School of Medicine

Date Issued 1996-12

File Version Version of Record

Access Rights open access

Relations

[ISSN]0513-1812

[NCID]AA00594272

Schools 医学部