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Involvement of serotonergic neuronal systems in the estrogen-induced afternoon prolactin surge : time-dependent changes in serotonergic neuronal activities in discrete brain nucllei

山口医学 Volume 36 Issue 3 Page 145-155
published_at 1987-06
Title
Estrogenにより誘発されるProlactin Surgeに対するSerotonin神経系の関与 : 脳部位別における時間依存性のSerotomin神経活動の変化
Involvement of serotonergic neuronal systems in the estrogen-induced afternoon prolactin surge : time-dependent changes in serotonergic neuronal activities in discrete brain nucllei
Creators Hirano Hitoshi
Source Identifiers
In this study, the involvement of the serotonergic neuronal systems in the estrogen-induced afternoon prolacin (PRL) surge was investigated. The induction of the afternoon PRL surge was confirmed using blood samples collected by both catheter and decapitation in the ovariectomized (OVX) estradiol (E_2)-treated rats. The contents of serotonin (5-HT) and 5-hydoroxyindole acetic acid (5-HIAA) in the following brain nuclei at 0900, 1500, and 1800 h were measured simultaneously using HRLC-ECD method [medial preoptic nucleus (POM), anterior hypotharamic nucleus (AH), suprachiasmatic nucleus (SCN), ventromedial (VM), and dorsomedial (DM) hypothalamic nuclei, arcuate nucleus (ARC), periventricular hypothalamic nucleus (PE), amygdala (AM), dorsal (RD) and medial (RM) raphe nuclei]. In OVX vehicle-injected rats, significantly lower were the contents both of 5-HT in any nuclei and of 5-HIAA in any nuclei excluding the PE and AM at 1800 h
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1987-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部