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Changes of Glutathione S-transferase during Initiation and Promotion of Hepatocarcinogenesis in Rats

山口医学 Volume 33 Issue 6 Page 419-424
published_at 1984-12
Title
ラット肝発癌過程におけるgluathione S-transferaseの動態 : initiationとpromotionの過程において
Changes of Glutathione S-transferase during Initiation and Promotion of Hepatocarcinogenesis in Rats
Creators Ogino Masaaki
Source Identifiers
The activities of glutathione S-transferase (GST) in rat liver cytosol were investigated sequentially during initiation and promotion of hepatocarcinogenesis by means of the experimental model of Solt and Farber. The results suggested that both diethylnitrosamine and 2 -fluorenylacetamide induced the activity of GST. It was also found that the induced enzymic levels of GST were suppressed by partial hepatectomy and was considered that the suppression of GST was a reasonable phenomenon to hepatocarcinogenesis.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1984-12
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部