Contents Menu

Experimental Study on the Mechanism of Action of Nerve Root Infiltration for Lumbosacral Radicular Pain

山口医学 Volume 41 Issue 1 Page 113-121
published_at 1992-02
Title
腰仙部神経根症状に対する根ブロックの効果発現機序に関する実験的研究
Experimental Study on the Mechanism of Action of Nerve Root Infiltration for Lumbosacral Radicular Pain
Creators Otani Takeshi
Source Identifiers
Creator Keywords
腰仙部神経根症状 神経根ブロック クモ膜絨毛
While the usefulness of nerve root infiltration (NRI) for lumbosacral radicular pain has been eatablished clinically, the mechanism of action of NRI is not elucidated yet. In this study, NRI was performed on monkeys to elucidate the mechanism of action of NRI from the morphological point of view. At first the fine structure of the connective tissue of the lumbar spinal nerve root was evaluated histologically. Secondly the location of Pelican ink injected with a contrast medium was investigated. As a result, the structure of the connective tissue of the spinal nerve root of monkeys was quite similar to humans. In addition, arachnoid villi were found near the subarachnoid angle. Furthermore, some ink was found in the nerve root near the subarachnoid angle while most of it was in the epiradicular space around the nerve root sleeve. These findings strongly suggested that local anesthetics injected into the epiradicular sapce ascended in a tubular fashion through the epidural space, and then some entered the nerve root at the subarachnoid angle via arachnoid villi acting as a pathway from the subarachnoid space to the epidural space.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1992-02
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部