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Clinical and Pathological Analysis of Patients with Synchronous Liver Metastases from Colorectal Cancer

山口医学 Volume 42 Issue 6 Page 365-369
published_at 1993-12
Title
大腸癌における同時性肝転移症例の検討
Clinical and Pathological Analysis of Patients with Synchronous Liver Metastases from Colorectal Cancer
Creators Oka Masaaki
Creators Uchiyama Tetsuji
Creators Shimizu Ryoichi
Creators Nishida Minekatsu
Creators Hazama Shouichi
Creators Suzuki Takashi
Source Identifiers
Creator Keywords
大腸癌 同時性肝転移 肝切除 肝動注療法 遠隔成績
Out of 511 patients with colorectal cancer, 39 patients with synchronous liver metastases were retrospectively studied. Ten patients underwent hepatic resection (RH group), 16 patient did not have hepatic resection (NRH group), and 13 patients had peritoneal dissemination (HP group). RH group including 5 HI cases underwent curative resection for colorectal primaries. The median survival time in RH group, NRH group, and HP group was 26.3 months, 7.7 months, and 8 months, respectively, with the survival curves differing significantly (p<0.03). In patients with resection with colorectal primaries, the median survival time in RH group, NRH group and HP group with systemic immunochemotherapy was 17.3 months, 6.8 months, 5.6 months, respectively and the median survival time in three groups with intrahepatic therapy was 39.2 months, 12.2 months, and 12 months, respectively. The survival rate in RH with intrahepatic therapy was significantly greater than that of other groups (p<0.05). However, the prognosis of RH group with systemic therapy was identical to other group. At present , hepatic resection with postoperative intrahepatic therapy for colorectal metastases may provide the only potential method of salvage.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1993-12
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部