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A New Hepatic Test based on Onservation of Altered Membrane Properties of Erythocytes : An Aplication of Coil Planet Centrifugation to Clinical Medicine

山口医学 Volume 23 Issue 1-2 Page 67-74
published_at 1974-06
Title
赤血球膜物性の変化に着目した新しい肝機能検査法 : Coil Planet Centrifugeの応用
A New Hepatic Test based on Onservation of Altered Membrane Properties of Erythocytes : An Aplication of Coil Planet Centrifugation to Clinical Medicine
Creators Kitajima Kazuhiko
Source Identifiers
The emolysis band appering on the helical centrifuge tube (”coil”) in coil planet centrifugation was shifted toward the side of lower osmolarity in hepatobiliary disorders. The rate of detection of hepatic dysfunction by the shifted hemolysis band was about 80 per cent, and false positive result in nonhepatobiliary diseases was 10 per cent. The mechanism by which the hemolysis band was bisplaced was studied, and it became evident that the ”Estersturz”. The mean shift of the hemolysis band was evident in parallel with the grade of dysfunction and damage of the hepatobiliary system, e.g. the average bias was distincter in liver cirrhosis than in hepatitis. Sequentially repeated tests on the same patients disclosed the bisa of the hemolysis band to very in satisfactorily good correlation with the advance and the recession of clinical manifestation. Accordingly, the coil planet centrifion is conceived to provide a usuful measure as a hepatic test equivalent to the estimation of ”Estersturz”. It is particularly reliable when patients are followed up.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1974-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部