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Mini-transplant and imatinib mesylate were temporarily effective in a patient with ph1 positive acute lymphoblastic leukemia which had been refractory to conventional chemotherapy

山口医学 Volume 51 Issue 6 Page 193-198
published_at 2002-12-31
B030051000602.pdf
[fulltext] 516 KB
Title
ミニ移植およびImatinib Mesylateが一時的に有効であった化学療法不応性フィラデルフィア染色体陽性急性リンパ性白血病の1症例
Mini-transplant and imatinib mesylate were temporarily effective in a patient with ph1 positive acute lymphoblastic leukemia which had been refractory to conventional chemotherapy
Creators Tominaga Takayuki
Creators Fukuda Naofumi
Creators Nakamori Yoshitaka
Creators Shimohakamada Yoko
Creators Taguchi Akihiko
Creators Miyazaki Mutsuko
Creators Shinohara Kenji
Source Identifiers
Creator Keywords
Ph1陽性ALL ミニ移植 Imatinib Mesylate
Mini-transplant was performed in a patient with Philadelphia chromosome (Ph1) positive acute lymphoblastic leukemia (ALL) which had been refractory to repeated courses of chemotherapy. Decrease of leukemic cells and mixed chimerism were observed during a first month. However, leukemic cells increased thereafter, and donor leukocyte infusion(DLI) was ineffective. Subsequently, Imatinib Mesylate was administered and leukemic cells decreased for 2 months, however lekemic cells increased thereafter. These treatments were temporarily effective for Ph1 positive ALL which was refractory to conventional chemotherapy. The improvement of these treatment strategies and accumulation of these cases are necessary.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 2002-12-31
Rights
本文データは山口大学医学会の許諾に基づきCiNiiから複製したものである()
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1731
[NCID]AN00243156
[isVersionOf] [NAID]http://ci.nii.ac.jp/naid/110002773756/