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Antileptospiral Activity of Several Antibiotics : Part 1. Results in vitro Examination

山口医学 Volume 34 Issue 5 Page 393-398
published_at 1985-10
Title
諸種抗生剤の抗レプトスピラ活性 : 第1報 諸種抗生剤のin vitro試験
Antileptospiral Activity of Several Antibiotics : Part 1. Results in vitro Examination
Creators Oie Shigeharu
Source Identifiers
The in vitro activity of 17 antibiotics against five serovar strains of the genus Leptospira was determined. Cefotaxime and ceftizoxime were found to be more effective than other agents such as penicillin G or streptomycin in tests for minimal bactericidal concentrations, the value being from 0.1 to 25μg/ml. Also, cefotaxime at a concentration of 25μg/ml killed each L. copenhageni of various age within 48 hours while penicillin G (25units/ml) did not kill within five days. On the other hand, fosfomycin did not show the inhibitory action against Leptospira, indicating that this drug was hopeful to be an agent for the selective cultivation of Leptospira from contaminated materials.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1985-10
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部