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Pathological Study on the Marginal Zone of the Spleen. Behavior of Marginal Zone to the Intravenously Injected Materials

山口医学 Volume 27 Issue 2 Page 121-134
published_at 1978-06
Title
脾濾胞周辺帯の病理学的研究 静注意物に対する周辺帯領域の態度
Pathological Study on the Marginal Zone of the Spleen. Behavior of Marginal Zone to the Intravenously Injected Materials
Creators Onishi Hiromi
Source Identifiers
Marginal zone of normal mice and treated mice with intravenous injection of four materials were studied on light microscopy. 1) The marginal zone of normal mice was shown as pale band between white pulp and red pulp. In the marginal zone, there were many cells which seemed to be corresponded to medium-sized lymphocytes. There ware small lymphocytes and reticulum cells in a moderate number in the marginal zone, while only a few macrophages were interspersed. Histochemically, acid phosphatese- and non-specific esterase-were arranged in a ring at the periphery of the white pulp, while a few metalophils were seen in the marginal zone. In alkaline phoshatase reaction, the cells, of which enzyme activity was lesser than that of endothelial cells, were moderately detected in the marginal zone. 2) Carbon, polystyrene latex, saccharated iron oxide and houseradish peroxidase (HrP) were intravenously injected into normal mice. In addition, HrP was intravenously injected the mice immunized with HrP. According to the finding that larger particles tended to stay longer in the marginal zone, the author suspected that the size of injected particles played an important role on the stagnation in the marginal zone.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1978-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部