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Monoclonal Antibody to Tumor-Antigen TA-4 of Squamous Cell Carcinoma

山口医学 Volume 35 Issue 1 Page 11-15
published_at 1986-02
Title
扁平上皮癌関連抗原TA-4のモノクローナル抗体に関する研究
Monoclonal Antibody to Tumor-Antigen TA-4 of Squamous Cell Carcinoma
Creators Nagaya Toshio
Source Identifiers
The present paper demonstrates the production of a monoclonal antibody against TA-4, a tumor-antigen of squamous cell carinoma of the uterine cervix. Hybridoma clones were prepared by fusions of the mouse myloma cell line P3U1 with spleen cells of BALB/c mice immunized with purified TA-4. One monoclonal antibody, which showed the highest titer was selected for further analyses of its characteristics. The antibody belonged to IgG class, and immunohistochemical studies with malignant and non-malignant tissues showed that the antibody specifically directed to TA-4. The monoclonal antibody would thus be useful for further inverstigations regarding TA-4.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1986-02
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部