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Evaluation of clinical parameters in 17 paraquat intoxicated cases

山口医学 Volume 40 Issue 4 Page 473-480
published_at 1991-08
Title
パラコート中毒17例の臨床学的検討
Evaluation of clinical parameters in 17 paraquat intoxicated cases
Creators Kuroda Seiko
Creators Nakamura Kumiko
Creators Shimizu Kiyomi
Creators Muranaka Kenji
Creators Matayoshi Yasutoshi
Creators Kamei Toshihiko
Creators Tamura Hisashi
Creators Shigetomi Michio
Source Identifiers
We have experienced 17 cases of paraquat poisoing in the past 7 years. After admission, the patients had been vigorously treated with blood purification (hemodialysis, direct hemoperfusion, and continuous hemofiltration), gastro-intestinal lavage with large amount of fluid, administration of steroids, ascorbic acid, tocopherol and glutatuion. Ten patients, however, died of circulatory failure within first day and remaining 6 patients developed actue cardio-respiratory failure and then finelly died of multiple organ failure until 10th hospital day. Only one case survived. In all dead cases, respiratory dysfunction in 15 patients, renal dysfunctuin in 11, hepatocellular injury in 10, pancreatitis in 9, disseminated intravascular coagulation in 7 were noticed. High mortality in this present study indicates the secerity and poor prognosis of paraquat poisoing in spite of the prompt initiation of above treatment.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1991-08
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部