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Study of an Intravenous Fat Tolerance Test with Intralipid Rate. -Evaluation of Fractional Turnover Rate of ntralipid Rate and Post Heparin Lipolytic Activity-

山口医学 Volume 25 Issue 1 Page 25-34
published_at 1976-03
Title
経静脈的脂肪負荷試験の研究 Intralipid Fractional Turnover Rate の臨床的意義と Post Heparin Lipolytic Activity との関連について
Study of an Intravenous Fat Tolerance Test with Intralipid Rate. -Evaluation of Fractional Turnover Rate of ntralipid Rate and Post Heparin Lipolytic Activity-
Creators Murakami Kohichi
Source Identifiers
Clinical entity of the K2 Value (triglyceride fractional turnover rate) obtained by Intravenous Fat Tolerance Test with Intratipid rate has been investigated with reference to PHLA (post heparin lipolytic activity). After intravenous injection of Intralipid rate, FFA (free fatty acid in sera), especially linolelc acid composing large part of Intralipid rate triglyceride, increases according to intravascular lipolysis, and disappearans of the increased FFA delays in type Ⅱb or type Ⅳhyperlipidemia, in whom k2 is abnormally low althoughPHLA is normal. Statistical analysis indicates an inverse partial correlation between K2 and fasting triglyceride level, and between K2 and age, but no partical correlation between K2 and PHLA is found. It is suggested by Multiple Regresion Analysis or Principle Component Analysis that the variation of K2 is closely related to serum triglyceride level and degree of obesity, while PHLA related to serum albumin level. It is quite possible that K2 reflects abnormality of lipid transport and K2 is, at least partly, independent of PHLA, and that also characteristic clinical informations are given by K2 measurement.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1976-03
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部