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Clinical significance ^<123>I-IMP single photon emission computed tomography in detecting regional cerebral blood flow

山口医学 Volume 38 Issue 6 Page 457-461
published_at 1989-12
Title
^<123>I-IMP single photon emission computed tomography (SPECT) の臨床的有用性の検討 : Xe-CT 脳血流測定との対比を中心として
Clinical significance ^<123>I-IMP single photon emission computed tomography in detecting regional cerebral blood flow
Creators Shiroyama Yujiro
Creators Nakayama Hisato
Creators Takasago Teiichi
Creators Tamashita Tetsuo
Creators Abiko Seisho
Creators Ito Haruhide
Creators Nishihara Sadamitsu
Creators Utsumi Hiromoto
Creators Yamada Norimasa
Source Identifiers
In order to estimate the N-isopropy- (I-123) p-Iodoamphetamine (^<123>I-IMP) single-photon-emission-computed tomography (SPECT) and cold Xenon CT, Cerebral blood flow (CBF) by means of both methods were measured almost simultaneously in 13 patients. The patients (10 males and 3 female) showed an age distribution from 33 to 69 years (mean=57.4 years). Eleven patients had cerebral infarction and the other two patients had cerebral hemorrhage. All oatients have been at the choronic stage. ^<123>I-IMP was utilized for SPECT using a rotating gamma-camera system. The uptakes of ^<123>I-IMP were counted for 2030 min and again 3-4 hours after the injection. The CBF by Xe-CT was mesured by means of Xe gas inhalation method. The results were as follows : 1) In the correlation of L/R ratio between ^<123>I-IMP-SPECT and Xe-CT, the ratin of ^<123>I-IMP uptake count correlated to the CBF ratio in Xe-CT. 2) The diffuse low CBF areas may be well visualized by SPECT rather than by CT-scan. 3) CBF image of ^<123>I-IMP-SPECT could be useful to evaluate cerebro-vescular diseases. Moreover, it may provide some insights into the pathophysiology of cerebral remote effect and vaibility.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1989-12
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部