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Interaction of Antibiotics with Nucleic Acids

山口医学 Volume 23 Issue 1-2 Page 1-6
published_at 1974-06
Title
核酸と抗生物質との相互反応 : 交叉泳動法による観察
Interaction of Antibiotics with Nucleic Acids
Creators Hashimoto Takao
Creators Hirozane Toshio
Source Identifiers
By means of the cross electrophoresis, interaction of antibiotics eith nucleic acids was studied. From the cross diahrams, it was elucidated that the various antibiotics were able to interact with RNA and DNA. Streptomycin, tetracyclines, and erythromycin combined so tightly with the nucleic acids that the latters precipitated on the line of antibiotics. Chloramphenical combined also with the nucleic acids and the mobility of the latters retaeded strangly. On the other hand, in the cases of penicillin and novobiocin interaction was not demonstrated from the cross diagrams. In regaed to RNA and DNA, no difference of the interaction with antibiotics was observed.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1974-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部