Methemoglobin and serum free hemoglobin concentrations before and after 3 km running at differential running speed

血中メトヘモグロビン濃度および血清ヘモグロビン濃度に及ぼす運動強度の影響

Methemoglobin and serum free hemoglobin concentrations before and after 3 km running at differential running speed

Creators Miyoshi Naoko

Creators Kawano Toshisada

Creators Shiota Masatoshi

The present study was carried out to investigate the effect of exercise-induced oxidative stress on methemoglobin (Met-Hb), serum free hemoglobin (Hb) and lipoperoxide concentrations before and after 3 km run at differential running speed.Met-Hb concentration in runners was higher than that in untrained subjects at rest, whereas
RBC (red blood cell) count and Hb concentration were lower in runners than those in untrained subjects. No significant changes of serum free Hb and lipoperoxide concentrations occurred. Serum free Hb concentration was found to decrease at low running speed (40%V4 O2max), and to increase at high running speed (80%V4 O2max), although Met-Hb concentration did not change. Similarly, blood lactate concentration decreased at low running speed and increased at high running speed. These results suggest that hemolysis to the red blood cells during running is caused by footstrike and fragility of RBC membrane, and partly oxidative stress associated with running at more than 80%V4 O2max.

[ISSN]0286-0597

[NCID]AN00240238