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Prefrontal abnormality in children with adhd during cognitive interference control : a functional nirs study

The bulletin of the Yamaguchi Medical School Volume 61 Issue 3-4 Page 37-47
published_at 2014
A050061000302.pdf
[fulltext] 1.79 MB
Title
Prefrontal abnormality in children with adhd during cognitive interference control : a functional nirs study
Creators Nakashima Mami
Creators Matsuo Koji
Creators Hashimoto Akiko
Creators Nakano Masayuki
Creators Fujii Yuko
Creators Matsushige Takeshi
Creators Egashira Kazuteru
Creators Matsubara Toshio
Creators Nishida Atsushi
Creators Ichiyama Takashi
Creators Sugiyama Shinsaku
Creators Watanabe Yoshifumi
Source Identifiers
Creator Keywords
attention-deficit/hyperactivity disorder dorsolateral prefrontal cortex hemodynamic response multi-source interference near-infrared spectroscopy
Aim: Children with attention-deficit/hyperactivity disorder (ADHD) show cognitive impairments such as disrupted attention and impaired learning and memory. The multi-source interference task (MSIT) combines multiple dimensions of cognitive interference and recruits the cingulo-frontal-parietal cognitive/attention network. The aim of this study was to determine whether children with ADHD show fronto-parietal dysfunction during the MSIT by using functional near-infrared spectroscopy (NIRS). Methods: Nineteen boys with ADHD and 14 age- and IQ-matched controls were studied. We measured oxygenated hemoglobin concentration ([oxy-Hb]) changes in the fronto-parietal region by using a 46-channel functional NIRS imaging system. The behavioral performance and mean [oxy-Hb] of the two groups during the MSIT were compared.Results: The behavioral data of the MSIT were not significantly different between the two groups. Compared to the control group, the ADHD group showed higher [oxy-Hb] changes in the left dorsolateral prefrontal region (ADHD, 0.17 × 10^-1 ±0.11
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University School of Medicine
Date Issued 2014
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 大学院医学系研究科(医学) 医学部附属病院 大学教育機構