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A Case Report of Seuretin Therapy for Primary Sclerosing Cholangitis

The bulletin of the Yamaguchi Medical School Volume 41 Issue 1-2 Page 51-58
published_at 1994-06
A020041000108.pdf
[fulltext] 800 KB
Title
A Case Report of Seuretin Therapy for Primary Sclerosing Cholangitis
Creators Fukumoto Yohei
Creators Okazaki Muneko
Creators Kajii Nobuhiro
Creators Omura Ryosuke
Creators Hino Keisuke
Creators Yasunaga Mitsuru
Creators Okita Kiwamu
Source Identifiers
Creator Keywords
Brainstem Ischemia Recirculation Hyperperfusion Vasomotor center
Primary sclerosing cholangitis (PSC) is a liver disease which is characterized by fibrous stenosis of both intra- and extra-hepatic bile ducts. No definite therapy has been established yet and the prognosis is very poor. The patient had persistent jaundice for about five years and levels of the serum total bilirubin fluctuated from 14.2 to 33.4mg/dl (mean value 20.1mg/dl). In order to improve jaundice, secretin, one of gut hormones, was administered intravenously in a dose of 150 to 200 units. As a result, the serum bilirubin was significantly decreased for about 8 months as compared to levels one year before secretin administration. It seemed that secretin was effective to improve the prognosis. Secretin therapy for PSC is entirely new strategy and appears to be useful as a medical treatment before induction of curative therapy such as liver transplantation.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1994-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部