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Cell-Mediated Immunity in Cancer Patient (I)

山口医学 Volume 27 Issue 2 Page 169-172
published_at 1978-06
Title
癌患者の細胞性免疫能について(第一報)
Cell-Mediated Immunity in Cancer Patient (I)
Creators Kusumoto Shizuo
Source Identifiers
It has been reported that the cell-mediated immunity in cancer patient decreased and was related to clinical stage of cancer and prognosis. One of the indicaters of the grade of cell-mediated immunity is the blastoid transformation of peripheral lymphocytes by phytohemagglutinin (PHA). Quantitive evaluation of lymphocyte blastogenesis was made by incorporation of ^<3>H-thymidine in blastogenic lymphocytes cultured with PHA and recorded by “Stimulation Index” (S.I.). In lymphocyte response curve by PHA, S.I. value of cancer patients was about one-third of the healthy volunteers. The ratio of both S.I. was the biggest at the concentration of PHA of 5μl/ml. Average values of S.I. of healthy volunteers and cancer patients were 61.9 and 27.8, respectively. The S.I. of cancer patients was lower than healthy volunteers.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1978-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部