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Cell-Mediated Immunological Investigation on the Susceptibility to Infection in Handicapped Children

山口医学 Volume 27 Issue 2 Page 157-168
published_at 1978-06
Title
重症心身障害児の易感染性に関する細胞性免疫学的検討
Cell-Mediated Immunological Investigation on the Susceptibility to Infection in Handicapped Children
Creators Kamimura Teruo
Source Identifiers
One hundred and nine children handicapped mentally and physically were investigated by a cell-mediated immunological method on account of being particularly susceptible to infection in their routine life. PHA skin reaction was weak, but tuberculin test after BCG inoculation was nnormal. The children partivularly susceptiblie to upper respiratory infection showed a weaker PHA skin reaction and higher level of serum immunoglobulin than the other handicappted children. Rosette-forming lymphocytes and lymphocytes transformed in vitro by PHA stimulation were evaluated in the peripheral blood of 15 cases, and these kinds of lymphocytes were decreased. Cell-mediated responses, after subcutaneous immunization with inactivated influenza vaccine, were examined in 15 cases. Rosette-forming lymphocytes and PHA skin reaction were suppressed significantly during three to six weeks after the first immunization.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1978-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部