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Performance of an Automated Blood Cell Analyzer with Special Reference to Suspect Flags

The bulletin of the Yamaguchi Medical School Volume 42 Issue 1-2 Page 9-16
published_at 1995-12
A020042000102.pdf
[fulltext] 784 KB
Title
Performance of an Automated Blood Cell Analyzer with Special Reference to Suspect Flags
Creators Oba Yuzo
Source Identifiers
Creator Keywords
Complete blood counts (CBC) automated blood cell analyzer flow cytometry suspect flag definitive flag
Performance of the flag system of an automated blood cell analyzer, Coulter STKS, was evaluated. The suspect flags were insufficient for the correct detection of specific abnormalities. The presence of blasts was correctly signaled in most samples (84/86) only if they comprised 20% or more of white blood cells, for example. However, the segregation of blood samples with any important abnormalities (e.g. blasts ≧1%, nucleated red cells ≧1/200WBC, or neutrophils younger than band ≧5%) was possible by adoption of all suspect and definitive flags because abnormal findings in complete blood counts of a sample are mutually interdependent. Atypical lymphocytes and neutrophilic bands were more difficult to detect automatically.   The present data implies that the present-day strategy to reduce microscopic observation by screening all blood samples with automated white blood cell differential count on the specific purpose of blood cell analysis is highly desirable in selected cases, especially with regards to atypical or abnormal lymphocytes and monocytes.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1995-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部