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Effects of ATP Preparation Myoactin C on the Smooth Muscle

山口医学 Volume 26 Issue 3 Page 159-164
published_at 1977-12
Title
平滑筋におけるATP製剤”ミオアクチンC”の作用について
Effects of ATP Preparation Myoactin C on the Smooth Muscle
Creators Yamauchi Hisao
Creators Yasumoto Tatsuo
Creators Suenaga Tadahiro
Creators Yamanouchi Takashi
Source Identifiers
The author has studied the effects of ATP preparation MYOACTIN C on the smooth muscle (small intestine and carotid artery) physiologially. MYOACTIN C is composed of ATP, L-cystine and L-tyrosine, as fix combination drugs. Results of experiments. The author observed that ATP increased the tone of the smooth muscle at a low concentration and decreased it at a high concentration. The effect by L-tyrcsine or L-cystine was faint on the smooth muscle, but L-tyrosine+L-cystine made to fall the tone.Though some ATP preparatitons on the market showed a remarkable fall of tone strongly and decreased the phasic concentration amplitude. The effects of MYOACTIN C on the smooth muscle can be considered that they relate closely with L-Tyosine+L-cystine. The effects of MYOACTIN C are also investigated at the combined administration of tetrodotoxin (10^-6g/ml), phenoxybenzamin, an adrenargic nerve-blocker (5×10^-6g/ml), pimdolol (2×10^-6g/ml) and also atropin, a cholinergic blocker (5×10^-6g/ml) , respectively
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1977-12
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部