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Effect of pH on Blood Coagulation Tests, Olasma Prothrombin Time (PPT) and Partial Thromboplastin Time (PTT)

The bulletin of the Yamaguchi Medical School Volume 17 Issue 1-2 Page 153-162
published_at 1970-06
A020017000110.pdf
[fulltext] 359 KB
Title
Effect of pH on Blood Coagulation Tests, Olasma Prothrombin Time (PPT) and Partial Thromboplastin Time (PTT)
Creators Nakashima Koji
Creators Uno Kaoru
Source Identifiers
It was shown that the plasma pHs were not equal in routine coagulation tests and the values of the PPT and PTT were affected by pH. Optimal pH for the reaction as well as the storage stability of the PPT and the PTT was demonstrated by the adjustment of pH with blowing the CO2 and O2 gas mixture and with adding acid and alkali. Restoration of the plasma pH with buffer solution did not restore the activity of the PPT and the PTT. A discussion about the acid-base imbalance and the optimal pH was made.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1970-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部