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Prolymphocytic Leukemia : Report of a Case with Autopsy Findings

The bulletin of the Yamaguchi Medical School Volume 30 Issue 1 Page 47-53
published_at 1983-12
A020030000106.pdf
[fulltext] 2.05 MB
Title
Prolymphocytic Leukemia : Report of a Case with Autopsy Findings
Creators Okubo Masaki
Creators Hiroshige Yukio
Creators Kaku Kohei
Creators Kamei Toshiaki
Creators Ishiguro Norio
Creators Matsumoto Noboru
Creators Kaneko Toshio
Source Identifiers
Creator Keywords
Prolymphocytic Leukemia T-cell Combination Chemotherapy
A case of prolymhocytic leukemia, a rare variant of chronic lymphocytic leukemia, was reported with autopsy findings. The patient was a 65-year-old woman who was chinically characterized by huge splenomegaly, mid lymphadenopathy and red skin eruption due to leukemic cell infiltration. The leukemic cellls in the peripheral blood and in the bone marrow had pale bluish cytoplasm and one large prominent nucleolus. Transmission electron microscopy also revealed a chromatin structure intermediate between that of a mature lymphocyte and that of a lymphoblast. Surfase maker studies suggested T-cell origin. Irradia tion to the spleen and chemotherapy with cyclophosphamide. And vincristine failed to induce remission.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1983-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部