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The development of a variable threshold analysis method to identify clones linked the clinicopathological features in an array-based CGH : its application to colorectal cancer

The bulletin of the Yamaguchi Medical School Volume 56 Issue 3-4 Page 43-48
published_at 2009
A050056000304.pdf
[fulltext] 77.4 KB
Title
The development of a variable threshold analysis method to identify clones linked the clinicopathological features in an array-based CGH : its application to colorectal cancer
Creators Nakao Motonao
Creators Uchiyama Tetuji
Creators Adachi Jun
Creators Furuya Tomoko
Creators Oga Atsunori
Creators Kawauchi Shigeto
Creators Sasaki Kohsuke
Source Identifiers
Creator Keywords
array based CGH threshold
In an array-based CGH, the analytical results of an evaluation of an abnormal number of copies are substantially affected by the designation of a cut off value for the ratio of the fluorescence intensity. In this study, we developed an array-based CGH analysis method that enables the designation of an optimal cut off value adapted to the analysis. With this method, the threshold of each BAC clone fluctuates automatically depending on the number of samples in order to enable the identification of a BAC clone correlated with the clinicopathological parameters…
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University School of Medicine
Date Issued 2009
File Version Version of Record
Access Rights open access
Relations
[isVersionOf] [URI]http://ds.cc.yamaguchi-u.ac.jp/~bulletin/index.html
Schools 大学院医学系研究科(医学)