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Plateau Formation in Action Potential of Guinea-Pig Ureter

The bulletin of the Yamaguchi Medical School Volume 18 Issue 3-4 Page 59-68
published_at 1971-12
A020018000301.pdf
[fulltext] 569 KB
Title
Plateau Formation in Action Potential of Guinea-Pig Ureter
Creators Ohkawa Hiromichi
Source Identifiers
1. Effects of changes in the external calcium cancentration on the electrical and mechanical activity in smooth muscle of ureter of guinea-pig have been studied by means of the sucrose-gap method and the mechano-electronic transducer. 2. Within a range of excess calium between 4.4mM to 6.6mM, the amplitude and the frequency of action potential were reduced. The membrane potential was increased slightly. 3. Within a range of excess calcium between 11mM to 44mM, the action potential was diminished and the membrane potential was increased slightly. 4. Total absebce of excess calcium in the external solution inhibited the generation of action potential initially and then theplateau type action potential reappeared. The oscillatory potentials developed on the later phase of plateau with the exposure time. 5. In excess potassium and calcium-free solution, the duration of plateau of action potential was shortened and the spike diminished finally. 6. In both potassium and calcium-free solution, the generation of action potential was inhibited transiently and then the action potentials reappeared. The duration of reappeared action potentials was not changed. 7. In both sodium and calcium-free solution, replaced by sucrose, lithium or choline, the plateau type action potential was abolished immediately.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1971-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部