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Different Localization of Vitamin D Dissolved in Oil and in Water in the Rat Liver Revealed by Fluorescence Microscopy

Bulletin of the Faculty of Agriculture, Yamaguchi University Volume 24 Page 749-756
published_at 1973
Title
水性ビタミンD_3と油性ビタミンD_2の筋注によるラット肝臓内の分布のちがい
Different Localization of Vitamin D Dissolved in Oil and in Water in the Rat Liver Revealed by Fluorescence Microscopy
Creators Makita Takashi
Creators Kozono Tatuziro
Creators Morimoto Masatoshi
Creators Kiwaki Sukechika
Source Identifiers
With intramuscular injections of aqueous vitamin D_s, fluorescent spots were predominantly localized in the fat-storing cells of the hepatic sinusoid. None of the hepatocyte had any indication of intracellular storing of vitamin D even with 10 injections of 10,000 I. U. per 100g of body weight. On the other hand the injections of vitamin D_2 dissolved in oil appeared to be stored in the rat heparocytes. This difference in localization was evident after 3 injections or more of vitamin D. With over-dose injection of vitamin D the rats in the group of aqueous solution experiments looked quite similar to those in control group. While the rat in the group that was injected with vitamin D_2 dissolved in oil vecame lifeless. ....
Subjects
農学 ( Other)
Languages jpn
Resource Type departmental bulletin paper
Publishers 山口大学農学部
Date Issued 1973
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1715
[NCID]AN00244250
Schools 農学部