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Resting Potential of the Muscle-Cell in Toad's Stomach.

The bulletin of the Yamaguchi Medical School Volume 11 Issue 1 Page 9-16
published_at 1964-03
A020011000102.pdf
[fulltext] 562 KB
Title
Resting Potential of the Muscle-Cell in Toad's Stomach.
Creators Sakata Yozo
Source Identifiers
1. The membrane potential was studied with microelectrode techniques on muscle cells of an isolated strip of toad's stomach. The solutions in which the muscle cells of an isolated strip of toad's stomach. The solutions in which the muscle strip was immersed were Ringer's or sucrose solution, and the effects of a few autonomic stimulating agents were observed. 2. The potential values were statistically different between the pyloric portion and gastric body in both Ringer's and sucrose solution. In the former, they were 50.5±0.7 (standard error) mV at pyloric portion and 45.0±0.9mV at gastric body. If the tip potentials were corrected, these membrane potential would be 58.3±1.7 mV at pyloric portion and 52.9±1.5 mV at gastric body, respectively. It was likely that the junction potential at an indifferent electrode is negligible. 3. In isotonic sucrose solution, the measured potential was higher (membrane was hyperpolarized) than in Ringer's, and the factors concerning this phenomenon were discussed. 4. The effect of acetylcholine or barium chloride was responsible for the depolarization of muscle membrane. The effect of adrenaline on the muscle membrane was minor. 5. Although the muscle strip showed rhythmical contraction by adding acetylcholine (10-5) or barium chloride (4.4 mM~ 7.4mM) to the bathing Ringer's solution, the evident action potentials could not be recorded.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1964-03
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部