THE STABILIZING ACTION OF CHLORPROMAZINE ON AMPHIBIAN HEART
The bulletin of the Yamaguchi Medical School Volume 6 Issue 3
Page 107-114
published_at 1959-04-30
Title
THE STABILIZING ACTION OF CHLORPROMAZINE ON AMPHIBIAN HEART
Creators
Shibata Jiro
Source Identifiers
1. Effects of chlorpromazine were examined on excised toads heart by means of the mechanogramm and the microelectrode technique. 2. Within several minutes after the abministration of chlorpomazine ( 1×10?5g/ml ), the height of contraction and heart rate are lowered approximately in half a value of control. 3. On the heart pre-treated with chlorpromazine ( 1×10?5g/ml ), the conduction block by artificial procedures does not so easily occur comparaed with the non-treated. 4. The membrane potential is lowered by chlorpromazine, the lowering is more marked in the sinus region than the auricular muscle. 5. It is discussed that the stabilization by chlorpromazine may be carried out on the functional level lowered by the drug.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1959-04-30
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部